Patch 16.14 · ADC

Caitlyn against Vayne

Name: Caitlyn vs Vayne — 44.6% matchup win rate (patch 16.14) | Lanemaster
Creator: Lanemaster
License: https://lanemaster.gg/

Caitlyn wins 44.6% of the 65 direct matchups against Vayne this patch.

44.6%Caitlyn

65Games

55.4%Vayne

Best runes against Vayne

Lethal Tempo Precision + Sorcery

56.3%16 games

Lethal Tempo Precision + Inspiration

62.5%8 games

Champion

Caitlyn
Vayne

Other Caitlyn matchups

Enemy	Games	Win rate
Jhin	478	46.0%
Ezreal	421	51.8%
Yunara	284	54.9%
Kai'Sa	240	49.2%
Ziggs	234	43.6%
Lucian	206	49.0%
Tristana	182	51.6%
Viktor	182	53.8%

See all champions · See the tier list

Take this data into the client

Lanemaster applies runes, spells and picks automatically in champ select — from the same data on this page.

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Aggregated from Ranked Solo/Duo games at the top of the ladder (Challenger, Grandmaster and Master) on KR, EUW and NA. Updated 2026-07-29 · Patch 16.14.