Patch 16.14 · Top

Dr. Mundo against Vayne

Name: Dr. Mundo vs Vayne — 45.8% matchup win rate (patch 16.14) | Lanemaster
Creator: Lanemaster
License: https://lanemaster.gg/

Dr. Mundo wins 45.8% of the 142 direct matchups against Vayne this patch.

45.8%Dr. Mundo

142Games

54.2%Vayne

Best runes against Vayne

Grasp of the Undying Resolve + Inspiration

21.4%28 games

Grasp of the Undying Resolve + Inspiration

42.3%26 games

Champion

Dr. Mundo
Vayne

Other Dr. Mundo matchups

Enemy	Games	Win rate
Jayce	222	49.5%
Yone	195	41.0%
Aatrox	172	40.7%
Jax	146	50.0%
Ambessa	137	44.5%
Renekton	126	50.0%
Malphite	110	63.6%
Sion	105	60.0%

See all champions · See the tier list

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Lanemaster applies runes, spells and picks automatically in champ select — from the same data on this page.

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Aggregated from Ranked Solo/Duo games at the top of the ladder (Challenger, Grandmaster and Master) on KR, EUW and NA. Updated 2026-07-29 · Patch 16.14.