LANEMASTER
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Varus Vayne
Patch 16.14 · Top

Varus against Vayne

Varus wins 50.7% of the 69 direct matchups against Vayne this patch.

50.7%Varus
69Games
49.3%Vayne

Best runes against Vayne

Press the Attack
Press the Attack Precision + Resolve
Resolve
37.5%8 games
TriumphLegend: AlacrityLast Stand OvergrowthBone Plating Attack SpeedAdaptive ForceHealth Scaling
Lethal Tempo
Lethal Tempo Precision + Inspiration
Inspiration
50.0%4 games
Absorb LifeLegend: AlacrityCut Down Biscuit DeliveryCosmic Insight Attack SpeedAdaptive ForceHealth

Other Varus matchups

EnemyGamesWin rate
JhinJhin 88 52.3%
EzrealEzreal 73 58.9%
Kai'SaKai'Sa 54 50.0%

See all champions · See the tier list

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Lanemaster applies runes, spells and picks automatically in champ select — from the same data on this page.

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Aggregated from Ranked Solo/Duo games at the top of the ladder (Challenger, Grandmaster and Master) on KR, EUW and NA. Updated 2026-07-29 · Patch 16.14.