LANEMASTER
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Vayne
Patch 16.14

Vayne runes

4 rune pages with at least 100 games this patch, ranked by win rate.

62.3%Win rate
4Rune pages
1,009Games

Top

Lethal Tempo
Lethal Tempo Precision + Inspiration · Top
Inspiration
62.3%114 games
TriumphLegend: AlacrityCut Down Cash BackBiscuit Delivery Attack SpeedAdaptive ForceHealth
Lethal Tempo
Lethal Tempo Precision + Inspiration · Top
Inspiration
56.5%138 games
Absorb LifeLegend: AlacrityCut Down Triple TonicCosmic Insight Attack SpeedAdaptive ForceHealth
Lethal Tempo
Lethal Tempo Precision + Resolve · Top
Resolve
48.0%473 games
TriumphLegend: AlacrityCoup de Grace ConditioningOvergrowth Attack SpeedAdaptive ForceHealth Scaling

Vayne Top

ADC

Lethal Tempo
Lethal Tempo Precision + Resolve · ADC
Resolve
49.3%284 games
TriumphLegend: AlacrityCoup de Grace ConditioningOvergrowth Attack SpeedAdaptive ForceHealth Scaling

Vayne ADC

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Aggregated from Ranked Solo/Duo games at the top of the ladder (Challenger, Grandmaster and Master) on KR, EUW and NA. Updated 2026-07-29 · Patch 16.14.